NEW RESEARCH

Human-Centered AI: Culture as the Catalyst
for AI-enabled Growth

To turn AI into a true growth engine, organizations must expand beyond tech and tools and start thinking about culture. Our latest research reveals how aligning people, purpose and progress is the key to sustainable AI adoption.

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The Human Edge

There’s never been a more important time for organizations to be human.  AI has leapt from buzzword to boardroom priority—redefining roles, reshaping workflows and unlocking new levers for growth. But while the technology accelerates, the cultural transformation needed to support AI is lagging.

This new report builds on our ongoing research into human-centered transformation. We interviewed CEOs and CHROs from leading global companies to explore how AI is impacting culture and what leaders must do now to embed AI at the heart of their organizations.

To unlock AI’s full potential, organizations must take a holistic approach—embedding it across every layer, from strategy and systems to people and processes. A successful AI-enabled workforce strategy requires more than investment; it demands synchronized leadership, clear priorities and a strong cultural mandate.

Prophet’s Human-Centered Transformation Model (HCTM) frames the organization as a living system—with a DNA, Mind, Body and Soul—that must evolve in concert for real, sustainable impact. Our research shows that true transformation happens when culture, leadership and talent align—turning AI from a tool into a powerful engine for growth.

Four Key Levers of
Human-Centered AI

DNA: Aligning AI with Purpose and Values.
Organizational DNA defines purpose and anchors strategy. When AI is aligned with core values, it gains direction, momentum—and staying power.

Mind: Scale Skills for What’s Next.
AI demands new capabilities across the workforce. Equip employees with the skills and mindsets needed to adapt, grow and lead through change.

Body: Redesign How Work Gets Done.
AI is reshaping roles, systems and workflows. To scale transformation, organizations must rethink how work happens and make agility the norm.

Soul: Deepen Human Connection.
By removing routine tasks, AI allows employees to focus on meaning, creativity and connection. The result: stronger engagement and purpose-driven work.

The Future is Human-Centered AI

It’s time to move beyond fragmented experimentation and toward intentional transformation.

AI isn’t just about automation—it’s about reimagining how people work, connect and grow.

When embedded across the DNA, Mind, Body and Soul of an organization, AI becomes more than a tool. It becomes a catalyst for purpose-driven growth, empowered talent and lasting cultural change.